Medicinal Plants Extracts Impact on Oxidative Stress in Mice Brain Under the Physiological Conditions: the Effects of Corn Silk, Parsley, and Bearberry

Authors

  • Marijana Vranješ Emergency Centre, Clinical Centre of Vojvodina, Hajduk Veljkova 1, 21000 Novi Sad, Serbia
  • Dubravka Štajner Chemistry and Biochemistry Laboratory, Department of Field and Vegetable Crops, Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovića 8, 21000 Novi Sad, Serbia
  • Dejan Vranješ Emergency Centre, Clinical Centre of Vojvodina, Hajduk Veljkova 1, 21000 Novi Sad, Serbia
  • Bojana Blagojevic Chemistry and Biochemistry Laboratory, Department of Field and Vegetable Crops, Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovića 8, 21000 Novi Sad, Serbia http://orcid.org/0000-0002-5383-7491
  • Ksenija Pavlović Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia
  • Dubravka Milanov Scientific Veterinary Institute “Novi Sad”, Rumenački put 20, 21113 Novi Sad, Serbia http://orcid.org/0000-0003-1987-8211
  • Boris M. Popović Chemistry and Biochemistry Laboratory, Department of Field and Vegetable Crops, Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovića 8, 21000 Novi Sad, Serbia http://orcid.org/0000-0002-8525-3896

DOI:

https://doi.org/10.17344/acsi.2021.6885

Keywords:

corn silk, parsley, bearberry, brain, oxidative stress, antioxidants

Abstract

This study was performed to examine the effects of medicinal plant extracts of corn silk (Stigma maydis), parsley leaf (Petroselini folium), and bearberry leaf (Uvae ursi folium) on antioxidant status of the brain of experimental animals (mice) under the physiological conditions. Biological properties of these plants are insufficiently investigated and the aim was to explore their possible antioxidant effects that can alleviate oxidative damage of the brain tissue. Corn silk extract showed positive effect on activities of antioxidant enzymes in mice brain tissue. Parsley extract induced the increase in glutathione content and decrease of lipid peroxidation. Bearberry leaf extract induced catalase activity and decrease of hydroxyl radical content, while malonyldialdehide accumulation was maintained at the control level. Results obtained in this study support the use of corn silk, parsley and bearberry leaves as natural antioxidant sources in the prevention and treatment of brain tissue damages and different diseases caused by oxidative stress.

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Published

15.12.2021

Issue

Vol. 68 No. 4 (2021)

Section

Applied chemistry

License

Except where otherwise noted, articles in this journal are published under the Creative Commons Attribution 4.0 International License