Amperometric Enzyme-free Glucose Sensor Based on Electrodeposition of Au Particles on Polyaniline Film Modified Pt Electrode

Abstract

An amperometric non-enzymatic glucose sensor of high sensitivity was developed by
modification of Pt electrode with electrodeposition of Au particles on polyaniline film. The
Au particles were deposited under optimum growth conditions for maximum dispersion on
polymer film to achieve highly sensitive glucose sensor. The characterization of the electrode
and the analytical parameters were evaluated using chronoamperometry and cyclic
voltammetry techniques. The sensor showed wide linear range from 0.01–8 mM along with
swift response time of less than 5 s. Moreover, a high sensitivity of 113.6 A mM-1 cm-2 is
obtained along with low detection limits of 0.5 M. The sensor also showed high stability,
reproducibility, and repeatability. Furthermore, the sensor has shown high selectivity towards
glucose exclusively in the presence of interferents such as sucrose, uric acid, and ascorbic
acid. The practical applicability of the proposed sensor was confirmed from successful
analysis of glucose in different juice samples and these results were comparable to the
commercial glucose meter. Thus, our sensor stands promising non-enzymatic sensor for
routine analysis of glucose.