Synthesis of Novel cis-2-Azetidinones from imines and aclychloride using triethylamine

Authors

  • Handan Can Sakarya Department of Chemistry, Faculty of Arts and Science, Eskişehir Osmangazi University, 26480 Eskişehir
  • Aslı Ketrez

DOI:

https://doi.org/10.17344/acsi.2023.8451

Abstract

A novel series of cis-2-azetidinones 2(a-c ) was carried out by the cyclo addition reaction of imine 1(a–c ) and acyl chloride in dry dichloromethane at 0-5 oC using triphenylamine. The cyclo addition of the Schiff bases with chloroacetyl chloride resulted corresponding major product cis-2-azetidinone stereoisomers 2(a-c). The synthesized compounds were characterized by analytical and spectral (Infrared, 1H NMR, 13C NMR, and elemental analysis) data.

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Published

04.12.2023

Issue

Vol. 70 No. 4 (2023): Acsi

Section

Organic chemistry

License

Copyright (c) 1970 Handan Can Sakarya, Aslı Ketrez

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Except where otherwise noted, articles in this journal are published under the Creative Commons Attribution 4.0 International License