Efficient Synthesis of Spironaphthopyrano[2,3-d]pyrimidine-5,3’-indolines under Solvent-free Conditions Catalyzed by SBA-Pr-SO<sub>3</sub>H as a Nanoporous Acid Catalyst

Authors

  • Ghodsi Mohammadi Ziarani Department of Chemistry, Alzahra University, PO Box 1993893973, Tehran, Iran
  • Negar Lashgari School of Chemistry, College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran
  • Sakineh Faramarzi Department of Chemistry, Alzahra University, PO Box 1993893973, Tehran, Iran
  • Alireza Badiei School of Chemistry, College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran

Keywords:

Spironaphthopyrano[2, 3-d]pyrimidine-5, 3'-indoline, Isatin, Barbituric acid, Functionalized SBA-15, Green synthesis

Abstract

A green, simple one-pot synthesis of spironaphthopyrano[2,3-d]pyrimidine-5,3'-indoline derivatives by a three-component reaction of isatins, 2-naphthol, and barbituric acids under solvent-free conditions in the presence of SBA-Pr-SO3H has been accomplished. Sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) as a heterogeneous nanoporous solid acid catalyst was found to be an efficient and recyclable acid catalyst in this synthesis.

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Published

05.09.2014

Issue

Vol. 61 No. 3 (2014)

Section

Organic chemistry

License

Except where otherwise noted, articles in this journal are published under the Creative Commons Attribution 4.0 International License