Syntheses, X-Ray Single Crystal Structures and Biological Activities of Cobalt(III) Complexes with Reduced Schiff Base Ligands

Abstract

A new mononuclear cobalt(III) complex, [Co(HL¹)₂]Cl (1), derived from the reduced Schiff base 2,2'-((ethane-1,2-diylbis(azanediyl))bis(methylene))diphenol (H₂L¹), and a new dinuclear cobalt(III) complex, [Co₂(L²)₂]∙2H₂O (2), derived from the reduced Schiff base 6,6’-(2-hydroxypropane-1,3-diyl)bis(azanediyl)bis(methylene)bis(2-bromo-4-chlorophenol) (H₂L²), were synthesized and characterized by infrared and electronic spectroscopy, and single crystal X-ray diffraction techniques. The ligands were synthesized first, and then bound to the Co(III) centre. Compound 1 contains a mononuclear [Co(HL¹)₂]⁺ cation and a chloride anion. The cationic moiety possesses crystallographic inversion center symmetry. Compound 2 contains a dinuclear [Co₂(L²)₂] molecule and two water hydrate molecules. The Co atoms in the complexes are in octahedral coordination. Both complexes showed potential antimicrobial activity.