Vanadium(V) Complexes with Bromo-Substituted Hydrazones: Synthesis, Characterization, X-ray Crystal Structures and Antimicrobial Activity

Abstract

Two new V^V complexes with the bromo-substituted hydrazones N'-(3-bromo-2-hydroxybenzylidene)-3-hydroxy-4-methoxybenzohydrazide (H₂L¹), N'-(3-bromo-2-hydroxybenzylidene)-3,5-dimethoxybenzohydrazide (H₂L²), [VOL¹(OCH₃)(CH₃OH)] (1) and [VOL²(OCH₃)(CH₃OH)] (2), were synthesized and structurally characterized by IR, UV-Vis and ¹H NMR spectroscopy, as well as single-crystal X-ray determination. The V atom in the mononuclear complexes are six-coordinated in octahedral geometry. The free hydrazones and the complexes were studied on their antibacterial activity on S. aureus, B. subtilis, E. coli and P. fluorescence, and antifungal activity on C. albicans and A. niger. The bromo groups of the hydrazone ligands may increase their antibacterial activity.