Synthesis, Characterization and Crystal Structures of Oxidovanadium(V) Complexes with Schiff Base and Pyrone Ligands and Their Antimicrobial Activity

Abstract

Two oxidovanadium(V) complexes, [VOLL^a] (1) and [VOLL^b] (2), where L is the dianionic form of the Schiff base ligand 2-(((2-hydroxyethyl)imino)methyl)-6-methylphenol (H₂L), L^a and L^b are the deprotonated forms of 3-hydroxy-2-methyl-4H-pyran-4-one (HL^a) and 2-ethyl-3-hydroxy-4H-pyran-4-one (HL^b), respectively, have been prepared and characterized by elemental analyses, IR, UV−Vis, ¹H NMR and single−crystal X−ray crystallographic determination. The V atoms in the complexes are in octahedral coordination, with the Schiff base ligand mer-coordinated to the metal atoms through the phenolate O, imino N and hydroxyl O atoms, and with the pyrone ligands coordinated to the metal atoms through the two O atoms. The effect of the compounds on the antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans was studied.