Synthesis of Coumarins and 2,3-dihydroquinazolin-4(1H)-ones

Authors

  • Zahed Karimi-Jaberi Department of Chemistry, Firoozabad Branch, Islamic Azad University, P.O. Box 74715-117 Firoozabad, Fars, Iran
  • Leila Zarei Department of Chemistry, Firoozabad Branch, Islamic Azad University, P.O. Box 74715-117 Firoozabad, Fars, Iran

Keywords:

Coumarins, 2, 3-dihydroquinazolin-4(1H)-ones, trichloroacetic acid, solvent-free synthesis...

Abstract

Trichloroacetic acid was used as an efficient catalyst for the synthesis of coumarins from phenols and beta-ketoesters and in an efficient synthesis of 2,3-dihydroquinazolin-4(1H)-ones through the condensation of 2-aminobenzamide with aldehydes or ketones under solvent-free conditions. The remarkable advantages offered by this method are short reaction times, simple procedure, and an easy work-up without using any chromatographic methods.

Downloads

Published

22.10.2013

Issue

Vol. 60 No. 1 (2013)

Section

Organic chemistry

License

Except where otherwise noted, articles in this journal are published under the Creative Commons Attribution 4.0 International License