Expeditious, Four-Component Synthesis of 1,4-Dihydropyrano[2,3-c]Pyrazole Derivatives Catalyzed by Trichloroacetic Acid or Ceric Sulfate

Authors

  • Zahed Karimi Jaberi Department of Chemistry, Firoozabad Branch, Islamic Azad University, P.O. Box 74715–117 Firoozabad, Fars, Iran
  • Mohammad Mehdi Reyazo Shams Department of Chemistry, Firoozabad Branch, Islamic Azad University, P.O. Box 74715–117 Firoozabad, Fars, Iran
  • Baharak Pooladian Department of Chemistry, Firoozabad Branch, Islamic Azad University, P.O. Box 74715–117 Firoozabad, Fars, Iran

Keywords:

1, 4-Dihydropyrano[2, 3-c]pyrazole derivatives, Four-component reaction, Trichloroacetic acid, Ceric sulfate, Heterogeneous catalysts

Abstract

Two efficient and convenient procedures for the synthesis of 6-amino-3-methyl-1,4-diphenyl-1,4-dihydropyrano[2,3c]pyrazole-5-carbonitrile derivatives based on four-component reaction involving ethyl acetoacetate, phenylhydrazine, malononitrile, and various aromatic aldehydes using trichloroacetic acid or ceric sulfate as heterogeneous catalysts in excellent yields and short reaction times have been described.

Downloads

Published

22.10.2013

Issue

Vol. 60 No. 1 (2013)

Section

Organic chemistry

License

Except where otherwise noted, articles in this journal are published under the Creative Commons Attribution 4.0 International License