ZrOCl2/nano TiO2 as an efficient catalyst for the one pot synthesis of naphthopyranopyrimidines under solvent-free conditions

Authors

  • Javad Safaei-Ghomi University of Kashan
  • Mahboubeh Mohaqeq Islamic Azad University
  • Hossein Shahbazi-Alavi University of Kashan

DOI:

https://doi.org/10.17344/acsi.2015.1567

Keywords:

ZrOCl2/nano TiO2, heterogeneous catalyst, naphtho[1', 2', 5, 6] pyrano[2, 3-d] pyrimidine, one-pot, solvent-free

Abstract

ZrOCl2/nano-TiO2 has been used as an efficient catalyst for the preparation of naphtho[1',2':5,6]pyrano[2,3-d]pyrimidine derivatives by the three-component reaction of aldehydes, β-naphthol and 1,3-dimethylbarbituric acid. The advantages of the reaction are solvent-free conditions, short reaction times, easy workup, good to excellent yields, and cost-effective and reusable catalyst.

Author Biographies

Javad Safaei-Ghomi, University of Kashan

Department of Organic Chemistry, Faculty of Chemistry,

Mahboubeh Mohaqeq, Islamic Azad University

Department of Chemistry, Qom Branch

Hossein Shahbazi-Alavi, University of Kashan

Department of Organic Chemistry, Faculty of Chemistry

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Published

16.11.2015

Issue

Vol. 62 No. 4 (2015)

Section

Organic chemistry

License

Except where otherwise noted, articles in this journal are published under the Creative Commons Attribution 4.0 International License